Okabe, Hiroyuki’s team published research in Organic Letters in 2019-06-21 | CAS: 16332-06-2

Organic Letters published new progress about Chemoselectivity (of dehydration of amide group). 16332-06-2 belongs to class ethers-buliding-blocks, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, Product Details of C3H7NO2.

Okabe, Hiroyuki published the artcileAcceptor-Controlled Transfer Dehydration of Amides to Nitriles, Product Details of C3H7NO2, the main research area is palladium catalyzed transfer dehydration amide nitrile chloroacetonitrile water acceptor.

Palladium-catalyzed dehydration of primary amides to nitriles efficiently proceeds under mild, aqueous conditions via the use of dichloroacetonitrile as a water acceptor. A key to the design of this transfer dehydration catalysis is the identification of an efficient water acceptor, dichloroacetonitrile, that preferentially reacts with amides over other polar functional groups with the aid of the Pd catalyst and makes the desired scheme exergonic, thereby driving the dehydration.

Organic Letters published new progress about Chemoselectivity (of dehydration of amide group). 16332-06-2 belongs to class ethers-buliding-blocks, name is 2-Methoxyacetamide, and the molecular formula is C3H7NO2, Product Details of C3H7NO2.

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem