Limberger, Jones published the artcileStereoselective synthesis of (E)-3,3-diaryl and (E)-3-aryl-3-aryloxy allylamines and allylalcohols from trans-cinnamyl chloride and alcohol, Formula: C8H11BO3, the main research area is diaryl allylamine regioselective diastereoselective preparation Suzuki coupling; aryl aryloxy allylamine regioselective diastereoselective preparation Ullmann coupling; allylalc diaryl regioselective diastereoselective preparation Suzuki coupling; aryloxy aryl allylalc regioselective diastereoselective preparation Ullmann coupling.
The regio and stereoselective synthesis of (E)-3,3-diaryl and (E)-3-aryl-3-aryloxy allylamines and allylalcs was described. The starting materials were the non-expensive com. available cinnamyl alc. and chloride. The bromination/dehydrobromination sequence furnished the (E)-3-bromo-3-phenylallyl amines and alc. as single regioisomers and with high stereoselectivity (>98%). These vinyl bromides were used as substrates in cross-coupling reactions furnishing the arylated products with good to excellent yields and total E-configuration retention. Regio and stereospecifically trisubstituted olefins and vinyl ethers by Suzuki cross-coupling and Ullmann vinylation were produced.
RSC Advances published new progress about Allylic alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 127972-00-3 belongs to class ethers-buliding-blocks, name is 2-Methoxy-5-methylphenylboronic acid, and the molecular formula is C8H11BO3, Formula: C8H11BO3.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem