Ring opening and skeletal reconstruction of 3-vinyl benzofuranone-chromone synthons: catalyst-free access to skeletally-diverse 2-pyridone and optically active imidazoline derivatives was written by Wang, Wei-Na;Liu, Ren-Ming;Zhang, Lei;Liu, Xiong-Li;Dai, Yi-Feng;Yu, Zhang-Biao;Peng, Li-Jun. And the article was included in Organic & Biomolecular Chemistry in 2022.Product Details of 109-85-3 The following contents are mentioned in the article:
Herein the first example of ring opening and skeletal reconstruction of 3-vinyl benzofuranone-chromones as versatile synthons, which could react with ammonia or primary aliphatic amines as binucleophiles, for the eco-friendly and atom-economical synthesis of diverse and functionalized 2-pyridones with potential biol. activity in good to excellent yields (77-93%) was reported. When using optically active 1,2-diphenylethylenediamine as the binucleophile, the in situ generated 2-pyridone intermediates were successfully transformed to novel optically active functionalized imidazoline derivatives with high efficiency (up to 87% yield). In particular, this was the first report on the catalyst-free intramol. cyclization occurring between an amide and a primary aliphatic amine for the construction of imidazoline mols. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Product Details of 109-85-3).
2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Product Details of 109-85-3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem