Electrochemical TEMPO-Catalyzed Oxidative Ugi-Type Reaction was written by Pan, Na;Xinen Lee, Maegan;Bunel, Louis;Grimaud, Laurence;Vitale, Maxime R.. And the article was included in ACS Organic & Inorganic Au in 2021.Synthetic Route of C3H9NO The following contents are mentioned in the article:
Oxidative isocyanide-based multicomponent reactions (oxidative IMCRs) are very useful tools for the rapid construction of mol. diversity starting from readily available and stable substrates. Despite all their benefits, such multicomponent reactions are underdeveloped and strictly limited to 3-component processes. Indeed, in the presence of several reaction partners, the oxidation event needs to be rigorously chemoselective, which becomes incredibly more intricate as the number of reactive components increases. Nonetheless, authors could overcome this significant pitfall and reach the first oxidative Ugi-type 4-IMCR by capitalizing on a very mild and green TEMPO-catalyzed electro-oxidation process. Employing alcs. as aldehyde surrogates and in the notable absence of any supporting electrolyte, this transformation proved to be extremely chemoselective in the presence of an amine and was compatible with a wide range of alcs., amines, isocyanides, and carboxylic acids. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Synthetic Route of C3H9NO).
2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Synthetic Route of C3H9NO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem