Tandem defluorination/annulation of α-CF3 carbonyls with bis-nucleophiles: Stereodivergent synthesis of 2-alkylidene-1,3-heterocycles was written by Ma, Yangyang;Mao, Kuantao;Chen, Yuanjin;Lv, Leiyang;Li, Zhiping. And the article was included in Tetrahedron Letters in 2022.Recommanded Product: 2-Methoxyethylamine The following contents are mentioned in the article:
A practical protocol for the stereodivergent synthesis of 2-alkylidene-1,3-N,X-heterocycles (X = O, S, NR) from the reactions of α-CF3 carbonyls and bis-nucleophiles has been developed under metal-free and ambient conditions. The reaction proceeds via the tandem defluorination of α-CF3 carbonyls followed by sequential nucleophilic substitution with two heteroatoms of bis-nucleophiles in a stereodivergent manner. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Recommanded Product: 2-Methoxyethylamine).
2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: 2-Methoxyethylamine
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem