Synthesis of 1,5-disubstituted tetrazoles in aqueous micelles at room temperature was written by Abdessalam, Mohammed;Sidhoum, Madjid Ait;Zradni, Fatima-Zohra;Ilikti, Hocine. And the article was included in Molbank in 2021.Safety of 2-Methoxyethylamine The following contents are mentioned in the article:
The ongoing study is a Ugi-azide four-component reaction for the synthesis of 1,5-disubstituted tetrazole (1,5-DST), which involves an aldehyde, different amines, isocyanides, and as azide source trimethylsilyl azide (TMSN3), in water as solvent using as catalyst tetradecyltrimethylammonium bromide (TTAB) (10 mol%), which provides a hydrophobic micellar reaction site. This approach is a step toward a green chem. reaction of 1,5 disubstituted tetrazole. A series of 1,5-disubstituted tetrazoles is synthesized with a large substrate scope, leading to yields between 43% and 56%, which are compared afterwards with those obtained with methanol as solvent. This study involved multiple reactions and reactants, such as 2-Methoxyethylamine (cas: 109-85-3Safety of 2-Methoxyethylamine).
2-Methoxyethylamine (cas: 109-85-3) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of 2-Methoxyethylamine
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem