Copper-Catalyzed Synthesis of Hindered Ethers from α-Bromo Carbonyl Compounds was written by Zhou, Zhe;Behnke, Nicole Erin;Kurti, Laszlo. And the article was included in Organic Letters in 2018.Name: 4-Benzyloxyphenol The following contents are mentioned in the article:
In the presence of CuBr·SMe2 and tricyclohexylphosphine, α-bromo-α,α-disubstituted carboxamides and carboxylic acids underwent chemoselective etherification and thioetherification reactions with alcs. and thiols at ambient temperature without exclusion of water and air to yield the corresponding ether- and thioether-substituted carboxamides and carboxylic acids. The method was used to prepare a quinolinylmethylphosphonate intermediate for protease-activated receptor 1 (PAR-1) antagonists which was unstable to previous etherification methods. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Name: 4-Benzyloxyphenol).
4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Name: 4-Benzyloxyphenol
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem