Ni-Catalyzed Cross-Electrophile Coupling of Aryl Triflates with Thiocarbonates via C-O/C-O Bond Cleavage was written by Zhu, Zhaodong;Gong, Yuxin;Tong, Weiqi;Xue, Weichao;Gong, Hegui. And the article was included in Organic Letters in 2021.Application In Synthesis of 4-Benzyloxyphenol The following contents are mentioned in the article:
A synthesis of aryl thioesters RCOSR1 (R = Ph, 4-MeO2CC6H4, 4-BnOC6H4, etc.; R1 = n-hexyl, cyclohexyl, cyclopentyl, etc.) via nickel-catalyzed reductive coupling of aryl triflates with thiocarbonates was reported. Both electron-rich and -deficient aryl C(sp2)-O electrophiles as well as a class of O-tBu S-alkyl thiocarbonates were compatible with the optimized reaction conditions as evidenced by 49 examples. The reaction also proceeded with good chemoselective cleavage of the C-O bond with regard to thioesters. This work broadened the scope of nickel-catalyzed reductive cross-electrophile coupling reactions. This study involved multiple reactions and reactants, such as 4-Benzyloxyphenol (cas: 103-16-2Application In Synthesis of 4-Benzyloxyphenol).
4-Benzyloxyphenol (cas: 103-16-2) belongs to ethers. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of 4-Benzyloxyphenol
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem