Antimicrobial Properties of Corn Stover Lignin Fractions Derived from Catalytic Transfer Hydrogenolysis in Supercritical Ethanol with a Ru/C Catalyst was written by Kalinoski, Ryan M.;Li, Wenqi;Mobley, Justin K.;Asare, Shardrack O.;Dorrani, Masoumeh;Lynn, Bert C.;Chen, Xiaowen;Shi, Jian. And the article was included in ACS Sustainable Chemistry & Engineering in 2020.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol The following contents are mentioned in the article:
Converting lignin to value added products at high yields provides an avenue for making ethanol biorefineries more profitable while reducing the carbon footprint of products generally derived from petroleum. In this study, corn stover lignin was depolymerized by catalytic transfer hydrogenolysis (CTH) in supercritical ethanol with a Ru/C catalyst. The lignin derived bio-oil was then sequentially extracted utilizing hexane, petroleum ether, chloroform and Et acetate as solvents in order of less polar to polar and the subsequent bio-oils were characterized using GPC, GC/MS and HSQC NMR. Results show lignin derived compounds were sequentially extracted into groups depending on the solvent polarity. Antimicrobial properties of the bio-oils were screened against Gram-pos. (Bacillus subtilis, Lactobacillus amylovorus, and Staphylococcus epidermidis), Gram-neg. (Escherichia coli) bacteria and yeast (Saccharomyces cerevisiae) by examining microbial growth inhibition. Results show that CTH derived bio-oils inhibited all tested organisms at concentrations less than 3 mg/mL. Total monomer concentration and the presence of specific monomers (i.e., syringyl propane) showed correlations to antimicrobial activity, likely due to cell death or membrane damage. This study provides insights into using sequential extraction to fractionate lignin-derived compounds and correlations between the properties of the extracted compounds and their antimicrobial activity. A lignin-based bio-oil was prepared from catalytic transfer hydrogenolysis of purified corn stover lignin with ethanol and a ruthenium on carbon catalyst. Polar and nonpolar solvents were used to sequentially extract different compounds The raw bio-oil and sequential extraction fractions exhibited antimicrobial properties against Gram-pos./neg. bacteria and yeast, with activity related to total monomer content and specific monomers. This study involved multiple reactions and reactants, such as 4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol).
4-Hydroxy-3-methoxyphenethanol (cas: 2380-78-1) belongs to ethers. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Application In Synthesis of 4-Hydroxy-3-methoxyphenethanol
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