Gui, Jingjing; Cai, Xin; Chen, Lingyun; Zhou, Yuxin; Zhu, Wenjing; Jiang, Yuanrui; Hu, Min; Chen, Xiaobei; Hu, Yanwei; Zhang, Shilei published an article in 2021, the title of the article was Facile and practical hydrodehalogenations of organic halides enabled by calcium hydride and palladium chloride.Safety of 2-Methoxynaphthalene And the article contains the following content:
Herein, a convenient hydrodehalogenation method was described by employing less-explored calcium hydride as the reductant. A wide range of organic halides such as aromatic bromides RBr (R = 4-(dimethylamino)phenyl, 4-aminonaphthalen-1-yl, quinolin-5-yl, etc.), aromatic chlorides R1Cl (R1 = naphthalen-1-yl, 3-carboxy-5-methoxyphenyl, 2-[2-(cyclohexa-1,5-dien-1-yl)ethenyl]phenyl, etc.), aromatic triflates R2Otf (R2 = 2-methylquinolin-8-yl, 2-nitrophenyl, 2-acetylnaphthalen-1-yl, etc.), 1-(2-(4-bromo/chlorobutoxy)phenyl)ethan-1-one were efficiently and selectively reduced to obtain the corresponding hydrocarbons e.g., Phenyl(pyrrolidin-1-yl)methanone. More importantly, monodehalogenation of trihalomethyl compounds R3CXY2 (R3 = benzenesulfonyl, 3-oxo-1-phenyl-3-(thiophen-3-yl)propyl, N-(naphthalen-1-yl)carbamoyl, etc.; X = Br, Cl; Y = Br, Cl, F) in THF could provide various useful dihalomethyl products R3CHY2. The experimental process involved the reaction of 2-Methoxynaphthalene(cas: 93-04-9).Safety of 2-Methoxynaphthalene
The Article related to hydrocarbon preparation, aromatic halide hydrodehalogenation calcium hydride palladium chloride catalyst, General Organic Chemistry: Synthetic Methods and other aspects.Safety of 2-Methoxynaphthalene
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem