On September 16, 1993, James, Donald R.; Baker, Don R.; Mielich, Steven D.; Michaely, William J.; Fitzjohn, Steven; Knudsen, Christopher G.; Mathews, Christopher; Gerdes, John M. published a patent.Category: ethers-buliding-blocks The title of the patent was Preparation of arylindazoles and their use as herbicides. And the patent contained the following:
Title compounds I (R1 = H, halo; R2 = H, O2N, halo, alkyl, NC, alkylthio, alkylsulfinyl, alkylsulfonyl, alkoxy, AcNH, H2N; R3 = H, halo, haloalkyl, haloalkoxy, NC, H2N, R13OyS wherein R13 = alkyl, haloalkyl, y = 0-2; R4, R5, R6 = H, halo, O2N, HO, NC, alkyl, alkoximinoalkyl, hydroxyalkyl, haloalkyl, CHO, etc.; R7 = H, halo, alkyl, O2N; R8 = H, halo; X = N, R14C wherein R14 = H, halo, haloalkyl, NC, etc.) and salts thereof, are prepared 6-Imidazolol in DMF was reacted with K2CO3 followed by MeI to give 6-methoxyindazole which in DMF was treated with 3,5,4-Cl2FC6H2CF3 and K2CO3 to give I (R1 = R4 = R5 = R7 = R8 = H, R2 = Cl, R3 = F3C, R6 = MeO, X = ClC) (II) in preemergence application II at 4 kg/ha showed 100% herbicidal effect against green foxtail, watergrass, wild mustard, velvetleaf, etc. A large number of I were prepared and evaluated both pre- and postemergence. The experimental process involved the reaction of 4-Bromo-5-methoxy-2-methylaniline(cas: 152626-77-2).Category: ethers-buliding-blocks
The Article related to indazole aryl preparation herbicide, Heterocyclic Compounds (More Than One Hetero Atom): Other 5-Membered Rings, Two Or More Hetero Atoms and other aspects.Category: ethers-buliding-blocks
Referemce:
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Ether | (C2H5)2O – PubChem