On April 15, 2022, Yu, Jianfei; Zhu, Haowei; Zhang, Xumu; Chen, Gen-Qiang published an article.Computed Properties of 81616-80-0 The title of the article was Development of C2-Symmetric Chiral Diphosphine Ligands for Highly Enantioselective Hydrogenation Assisted by Ion Pairing. And the article contained the following:
A new series of C2-sym. chiral ferrocene-based diphosphino-ethane ligands termed as f-DPE, I (R = Ph, Me CH2Ph, 2-MeOC6H4, 3-MeOC6H4, 4-MeOC6H4) were developed. Assisted by the ion pairing interaction with the ligand, a wide scope of 2-substituted acrylic acids was hydrogenated to obtain chiral propanoic acids. with high yields and enantioselectivities. The well-known anti-inflammatory drugs ibuprofen, naproxen, and flurbiprofen could be synthesized efficiently. In addition, the synthetic utilities of the current method were demonstrated by gram-scale experiments The experimental process involved the reaction of (S)-2-(2-Methoxyphenyl)propanoic acid(cas: 81616-80-0).Computed Properties of 81616-80-0
The Article related to propanoic acid preparation enantioselective, acrylic acid hydrogenation chiral diphosphine ferrocene catalyst, sym chiral ferrocene diphosphinoethane ligand preparation catalyst and other aspects.Computed Properties of 81616-80-0
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Ether | (C2H5)2O – PubChem