Svejstrup, Thomas D.; Ruffoni, Alessandro; Julia, Fabio; Aubert, Valentin M.; Leonori, Daniele published an article in 2017, the title of the article was Synthesis of Arylamines via Aminium Radicals.Electric Literature of 321-28-8 And the article contains the following content:
Arylamines constitute the core structure of many therapeutic agents, agrochems., and organic materials. The development of methods for the efficient and selective construction of these structural motifs from simple building blocks is desirable but still challenging. We demonstrate that protonated electron-poor O-aryl hydroxylamines give aminium radicals in the presence of Ru(bpy)3Cl2. These highly electrophilic species undergo polarized radical addition to aromatic compounds in high yield and selectivity. We successfully applied this method to the late-stage modification of chiral catalyst templates, therapeutic agents, and natural products. The experimental process involved the reaction of 1-Fluoro-2-methoxybenzene(cas: 321-28-8).Electric Literature of 321-28-8
The Article related to arene aryl hydroxylamine aminium radical photocatalytic regioselective amination, arylamine preparation, n-arylation, aminium radicals, aryl amines, late-stage amination, synthetic methods and other aspects.Electric Literature of 321-28-8
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