Ethers lack the hydroxyl groups of alcohols. Without the strongly polarized O―H bond, ether molecules cannot engage in hydrogen bonding with each other. 530-59-6, formula is C11H12O5, Name is 3,5-Dimethoxy-4-hydroxycinnamic acid. Ethers do have nonbonding electron pairs on their oxygen atoms, however, and they can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. Product Details of C11H12O5.
Wang, Qi;Tang, Xin;Wen, Jingyu;Weng, Jingxian;Liu, Xiaowei;Dai, Lihong;Li, Junxin;Mu, Li research published 《 Arsenite phytotoxicity and metabolite redistribution in lettuce (Lactuca sativa L.)》, the research content is summarized as follows. Arsenic (As) contamination has become a global problem, especially in developing countries, where a significant percentage of the population depends on groundwater for drinking. Arsenic toxicity depends on its chem. form. Herein, we evaluated the phytotoxicity of arsenite [As(III)], including As accumulation and adverse physiol. responses (e.g., growth inhibition, oxidative stress, and metabolic disturbances). Furthermore, this result was compared with the mechanism of the phytotoxicity of arsenate [As(V)] that we previously explored. As accumulated mainly in the roots (29.33-88.73 mg/kg) of lettuce, only a small amount was transferred to the leaves (0.08-0.22 mg/kg); arsenic mainly existed in the form of As(III) in plants. As(III) was pos. correlated with Mn in the leaves and roots and neg. correlated with Ca in roots and Mg in leaves, consistent with the increase in SOD activity and the destruction of the chloroplast membrane. Plants responded differently to As(III) and As(V) in terms of the antioxidant response and metabolic response. CAT activity in leaves was reduced following As(III) exposure and increased upon As(V) exposure. Furthermore, As(III) decreased the levels of some products of the tricarboxylic acid cycle and induced abnormal metabolism of secondary metabolites, such as phenol and niacin. The present study explored arsenic accumulation induced by As(III), the related physiol. and biochem. responses and subsequent metabolite redistribution, and provided insights into the effects of different As species on plants.
Product Details of C11H12O5, Sinapinic acid is a chemical compound that is the dihydroxybenzoic acid derivative of sinapic acid. It has been shown to have anti-inflammatory properties in vitro and in vivo. Sinapinic acid inhibits the activity of various enzymes, such as cyclooxygenase (COX), lipoxygenase (LOX), and 5-lipoxygenase-activating protein (FLAP). It also decreases levels of adhesion molecules and downregulates inflammatory response genes. Sinapinic acid has been shown to reduce inflammation by inhibiting the formation of proinflammatory mediators, such as prostaglandin E2 or leukotriene B4, in endothelial cells and mammary epithelial cells.
Sinapic acid is a phenylpropanoid hydroxycinnamic acid with diverse biological activities. Sinapic acid inhibits collagen-induced human platelet aggregation by up to 70% in vitro (IC50 = 1.03 mM). It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS) free radicals with IC50 values of 8.3 and 5.4 μg/ml, respectively. Sinapic acid (200 μM) reduces colony formation of SW480 human colon carcinoma cells by 4-fold. It also inhibits colony formation of E. coli, S. enteritidis, and S. aureus on agar (MICs = 2.2, 2, and 1.8 mM, respectively). In vivo, sinapic acid (4 mg/kg, p.o.) increases the time spent in the open arms of the elevated plus maze by approximately 15% in mice, an effect that can be blocked by the GABAA receptor antagonists flumazenil and bicuculline. Sinapic acid is also commonly used as a matrix in protein mass spectrometry.
Sinapic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.
Sinapic acid is an hydroxycinnamic acid derivative that occurs naturally in Brassicaceae species.
cis-Sinapic acid, also known as cis-sinapate or synapitic acid, belongs to the class of organic compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated. cis-Sinapic acid is considered to be a practically insoluble (in water) and relatively neutral molecule. Within the cell, cis-sinapic acid is primarily located in the cytoplasm. Outside of the human body, cis-sinapic acid can be found in common pea and pulses. This makes cis-sinapic acid a potential biomarker for the consumption of these food products.
Cis-sinapic acid is a 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid in which the double bond has cis-configuration. It has been isolated from the shoots of alfalfa. It has a role as a plant metabolite., 530-59-6.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem