Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 75148-49-1, name is 3-Bromobenzaldehyde Diethyl Acetal, A new synthetic method of this compound is introduced below., HPLC of Formula: C11H15BrO2
As shown in FIG. 2, 3.3 mmol of 3-bromobenzaldehyde diethanol and 3.8 mmol of nitrile ethyl acetate were mixed and diluted with ethyl acetate to 10 mL, and then the resulting solution was reacted by continuous flow at a flow rate of 1 mL / min. The device was pumped into the first HPLC column (containing 1 g PS-perazine) and the second HPLC column (containing 1 g PS-N-SO3) in sequence, and the first and second HPLC columns were immersed in an oil bath at 50 C. and reacted for 3 hours. After the reaction was completed, the HPLC column was rinsed with ethyl acetate, the product was collected, ethyl acetate was evaporated, and recrystallized from ethanol to obtain a solid product with a yield of 91%.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Huaqiao University; Xiong Xingquan; Liao Xu; (11 pag.)CN110818592; (2020); A;,
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