Ethers do have nonbonding electron pairs on their oxygen atoms, 530-59-6, formula is C11H12O5, Name is 3,5-Dimethoxy-4-hydroxycinnamic acid. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds. Formula: C11H12O5.
Mezni, Faten;Stiti, Boutheina;Fkiri, Sondes;Ayari, Faten;Slimane, Lassaad Ben;Ksouri, Riadh;Khaldi, Abdelhamid research published 《 Phenolic profile and in vitro anti-diabetic activity of acorn from four African Quercus species (Q. suber, Q. canariensis, Q. coccifera and Q. ilex)》, the research content is summarized as follows. In this investigation we studied the phenolic profile of acorn extracts from four Quercus species. We evaluated whether the phenolic compounds could inhibit the metabolism of carbohydrates. Four different Quercus species were studied; Q. suber, Q. canariensis, Q. coccifera and Q. ilex. The total phenolic content was determined using Folin-Ciocalteu′s reagent and its identification was conducted using HPLC-UVDAD. The α-amylase inhibition assay was performed using the sensitive agar diffusion method. Q. suber and Q. canariensis were characterized by the highest phenolic content (2950.98 mg EGA/g and 4380.69 mg EGA/g, resp.). Chlorogenic acid was identified as the major compound in extracts from Q. ilex, Q. coccifera and Q. suber. Whereas, Coumarin was determined as the major compound in Q. canariensis extract (44.65%).The application of Q. canariensis showed ahigher effect than that of the pos. control (43.42%). This inhibition is likely due to the high polyphenol content in the acorns of this species.
Formula: C11H12O5, Sinapinic acid is a chemical compound that is the dihydroxybenzoic acid derivative of sinapic acid. It has been shown to have anti-inflammatory properties in vitro and in vivo. Sinapinic acid inhibits the activity of various enzymes, such as cyclooxygenase (COX), lipoxygenase (LOX), and 5-lipoxygenase-activating protein (FLAP). It also decreases levels of adhesion molecules and downregulates inflammatory response genes. Sinapinic acid has been shown to reduce inflammation by inhibiting the formation of proinflammatory mediators, such as prostaglandin E2 or leukotriene B4, in endothelial cells and mammary epithelial cells.
Sinapic acid is a phenylpropanoid hydroxycinnamic acid with diverse biological activities. Sinapic acid inhibits collagen-induced human platelet aggregation by up to 70% in vitro (IC50 = 1.03 mM). It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) and 2,2′-azino-bis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS) free radicals with IC50 values of 8.3 and 5.4 μg/ml, respectively. Sinapic acid (200 μM) reduces colony formation of SW480 human colon carcinoma cells by 4-fold. It also inhibits colony formation of E. coli, S. enteritidis, and S. aureus on agar (MICs = 2.2, 2, and 1.8 mM, respectively). In vivo, sinapic acid (4 mg/kg, p.o.) increases the time spent in the open arms of the elevated plus maze by approximately 15% in mice, an effect that can be blocked by the GABAA receptor antagonists flumazenil and bicuculline. Sinapic acid is also commonly used as a matrix in protein mass spectrometry.
Sinapic acid analytical standard provided with w/w absolute assay, to be used for quantitative titration.
Sinapic acid is an hydroxycinnamic acid derivative that occurs naturally in Brassicaceae species.
cis-Sinapic acid, also known as cis-sinapate or synapitic acid, belongs to the class of organic compounds known as hydroxycinnamic acids. Hydroxycinnamic acids are compounds containing an cinnamic acid where the benzene ring is hydroxylated. cis-Sinapic acid is considered to be a practically insoluble (in water) and relatively neutral molecule. Within the cell, cis-sinapic acid is primarily located in the cytoplasm. Outside of the human body, cis-sinapic acid can be found in common pea and pulses. This makes cis-sinapic acid a potential biomarker for the consumption of these food products.
Cis-sinapic acid is a 3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid in which the double bond has cis-configuration. It has been isolated from the shoots of alfalfa. It has a role as a plant metabolite., 530-59-6.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem