Ajarul, Sk; Kayet, Anirban; Pati, Tanmay K.; Maiti, Dilip K. published an article in 2020, the title of the article was A competitive and highly selective 7-, 6- and 5-annulation with 1,3-migration through C-H and N-H – alkyne coupling.COA of Formula: C15H13NO And the article contains the following content:
A highly competitive and selective C-C and N-C cross-coupled 7-, 6- and 5-annulation was described utilizing 2-ethynylanilides to afford functionalized 1H-benzo[b]azepin-2(5H)-ones I [R1 = Me, Et, Ph, 4-O2NC6H4; R2 = Ph, 4-MeC6H4, 4-FC6H4, etc.; R3 = H, 7-Me, 7-Cl, 8-Cl], 2-quinolinones II [R4 = Me, Et, Ph, etc.; R5 = H, Ph, 4-O2NC6H4, etc.; R6 = H, 6-Me, 7-Cl, etc.] and 3-acylindoles III [R7 = Me, Et, Ph, 4-MeC6H4; R8 = Ph, 4-MeOC6H4, 4-BrC6H4; R9 = H, Me, Cl, Br] resp., with high yields and operational simplicity. Zinc chloride was found to be the smart catalyst for 7- and 5-annulation with 1,3-migration through C-H and N-H functionalization, resp., whereas mol. iodine performed the C-H functionalized 6-annulation with a non-conventional 1,3 H-shift. The mechanism was investigated by intermediate trapping, control and labeling experiments The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).COA of Formula: C15H13NO
The Article related to benzoazepinone selective preparation, alkynyl aniline dicarbonyl compound annulation zinc catalyst, quinolinone selective preparation, aniline dicarbonyl compound alkynyl annulation iodine catalyst, acylindole selective preparation, acyl alkynyl aniline annulation zinc catalyst and other aspects.COA of Formula: C15H13NO
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem