Vonnegut, Chris L.; Shonkwiler, Airlia M.; Khalifa, Muhammad M.; Zakharov, Lev N.; Johnson, Darren W.; Haley, Michael M. published an article in 2015, the title of the article was Facile Synthesis and Properties of 2-λ5-Phosphaquinolines and 2-λ5-Phosphaquinolin-2-ones.HPLC of Formula: 157869-15-3 And the article contains the following content:
Treatment of 2-ethynylanilines with P(OPh)3 gives either 2,2-diphenoxy-2-λ5-phosphaquinolines or 2-phenoxy-2-λ5-phosphaquinolin-2-ones under transition-metal-free conditions. This reaction offers access to an underexplored heterocycle, which opens up the study of the fundamental nature of the N:PV double bond and its potential for delocalization within a cyclic π-electron system. This heterocycle can serve as a carbostyril mimic, with application as a bioisostere for pharmaceuticals based on the 2-quinolinone scaffold. It also holds promise as a new fluorophore, since initial screening reveals quantum yields upwards of 40 %, Stokes shifts of 50-150 nm, and emission wavelengths of 380-540 nm. The phosphaquinolin-2-ones possess one of the strongest solution-state dimerization constants for a D-A system (130 Μ-1) owing to the close proximity of a strong acceptor (P:O) and a strong donor (phosphonamidate N-H), which suggests that they might hold promise as new H bonding hosts for optoelectronic sensing. The experimental process involved the reaction of 2-((4-Methoxyphenyl)ethynyl)aniline(cas: 157869-15-3).HPLC of Formula: 157869-15-3
The Article related to crystal structure optimized phosphaquinoline phosphaquinolinone preparation fluorescence dimerization, mol structure optimized phosphaquinoline phosphaquinolinone preparation fluorescence dimerization, alkynes, dimerization, fluorescent probes, phosphazenes, phosphorus heterocycles and other aspects.HPLC of Formula: 157869-15-3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem