On January 31, 2000, Coalter, Joseph N. III; Bollinger, John C.; Huffman, John C.; Werner-Zwanziger, Ulrike; Caulton, Kenneth G.; Davidson, Ernest R.; Gerard, Helene; Clot, Eric; Eisenstein, Odile published an article.Safety of 2-(2-(Vinyloxy)ethoxy)ethanol The title of the article was Coordinated carbenes from electron-rich olefins on RuHCl(PPri3)2. And the article contained the following:
Dehydrohalogenation of RuH2Cl2L2 (L = PPri3) gives (RuHClL2)2, shown to be a halide-bridged dimer by x-ray crystallog.; the fluoride analog is also a dimer. (RuHClL2)2 reacts with N2, pyridine and C2H4 (L’) to give RuHClL’L2, but with vinyl ether and vinyl amides, H2C:CH(E) [E = OR, NRC(O)R’] such olefin binding is followed by isomerization to the heteroatom-substituted carbene complex L2HClRu:CMe(E). The reaction mechanism for such rearrangement was established by DFT (B3PW91) computations, for C2H4 as olefin (it is endothermic), and the structures of intermediates are calculated for H2C:C(H)(OCH3) and for cyclic and acyclic amide-substituted olefins. It is found, both exptl. and computationally, that the amide O is bonded to Ru, with a calculated bond energy of ∼9 kcal mol-1 for an acyclic model. Less electron-rich vinyl amides or amines form η2-olefin complexes, but do not isomerize to carbene complexes. Calculated ΔE values for selected competition reactions reveal that donation by both Ru and the heteroatom-substituted X are necessary to make the carbene complex L2HClRu:C(X)Me more stable than the olefin complex L2HClRu(η2-H2C:CHX). This originates in part from a diminished endothermicity of the olefin → carbene transformation when the sp2 C bears a π-donor substituent. The importance of a hydride on Ru in furnishing a mechanism for this isomerization is discussed. The compositional characteristics of Schrock and Fischer carbenes are detailed, it is suggested that reactivity will not be uniquely determined by these characteristics, and these new carbenes RuHCl[C(X)CH3]L2 are contrasted to Schrock and Fischer carbenes. The experimental process involved the reaction of 2-(2-(Vinyloxy)ethoxy)ethanol(cas: 929-37-3).Safety of 2-(2-(Vinyloxy)ethoxy)ethanol
The Article related to crystal structure ruthenium hydrido dinitrogen carbene complex, mol structure ruthenium hydrido dinitrogen carbene complex, electron rich olefin ruthenium coordinated regioselective rearrangement, vinyl amide ether ruthenium coordinated regioselective rearrangement, density functional ruthenium coordinated olefin regioselective rearrangement and other aspects.Safety of 2-(2-(Vinyloxy)ethoxy)ethanol
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem