In 2022,Chu, Wen-Dao; Liang, Tian-Tian; Ni, Hao; Dong, Zhi-Hong; Shao, Zhihui; Liu, Yong; He, Cheng-Yu; Bai, Ruopeng; Liu, Quan-Zhong published an article in Organic Letters. The title of the article was 《Palladium-Catalyzed Intermolecular Asymmetric Dearomative Annulation of Phenols with Vinyl Cyclopropanes》.Synthetic Route of C7H8O2 The author mentioned the following in the article:
Herein, the Pd(0)-catalyzed intermol. asym. dearomative [3+2] annulation of phenols with vinyl cyclopropanes via in situ generated ortho-quinone methide intermediates was reported. A series of highly functionalized spiro-[5,6]bicycles, e.g., I which bear three contiguous stereogenic centers including one all-carbon quaternary were obtained with excellent stereoselectivities. D. functional theory (DFT) calculations indicated that the reactions were controlled by thermodn. In the part of experimental materials, we found many familiar compounds, such as m-Methoxyphenol(cas: 150-19-6Synthetic Route of C7H8O2)
m-Methoxyphenol(cas: 150-19-6) may be used in synthesis of:C(4) symmetric calix[4]resorcinarene, 2-nitroso-5-methoxyphenol, 6-methoxy-2(3H)-benzoxazoloneSynthetic Route of C7H8O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem