《Diastereoselective olefin amidoacylation via photoredox PCET/nickel-dual catalysis: reaction scope and mechanistic insights》 was written by Zheng, Shuai; Zhang, Shuo-Qing; Saeednia, Borna; Zhou, Jiawang; Anna, Jessica M.; Hong, Xin; Molander, Gary A.. Formula: C9H10O2 And the article was included in Chemical Science in 2020. The article conveys some information:
Synthesis of cyclic amides such as I via regio- and diastereoselective amidoacylation of unactivated olefins by using photoredox proton-coupled electron transfer (PCET)/Ni dual-catalysis was developed. Various acyl electrophiles were compatible, including alkyl- and aryl acyl chlorides and anhydrides, as well as in situ activated carboxylic acids. Hammett studies and other mechanistic experiments to elucidate features of the diastereoselectivity, a transient absorption study of the PCET step, as well as computational evidence, provide an in-depth understanding of the disclosed transformation. In the experiment, the researchers used many compounds, for example, 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Formula: C9H10O2)
2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).Formula: C9H10O2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem