Electric Literature of C9H10O2In 2020 ,《Photoinduced site-selective alkenylation of alkanes and aldehydes with aryl alkenes》 was published in Nature Communications. The article was written by Cao, Hui; Kuang, Yulong; Shi, Xiangcheng; Wong, Koi Lin; Tan, Boon Beng; Kwan, Jeric Mun Chung; Liu, Xiaogang; Wu, Jie. The article contains the following contents:
Herein, a photocatalytic method for the direct alkenylation of alkanes and aldehydes with aryl alkenes in the absence of any external oxidant were reported. A diverse range of commodity feedstocks and pharmaceutical compounds such as RHC=CHR1 [R = cyclopentyl, Ph, 3-ClC6H4, etc.; R1 = cyclohexyl, Ph, 4-OAcC6H4, etc.; stereo = cis, trans] were smoothly alkenylated in useful yields with the C-H partner as the limiting reagent. The late-stage alkenylation of complex mols. occurs with high levels of site selectivity for sterically accessible and electron-rich C-H bonds. This strategy relied on the synergistic combination of direct hydrogen atom transfer photocatalysis with cobaloxime-mediated hydrogen-evolution cross-coupling, which promises to inspire addnl. perspectives for selective C-H functionalizations in a green manner. In the experiment, the researchers used 2-(Benzyloxy)acetaldehyde(cas: 60656-87-3Electric Literature of C9H10O2)
2-(Benzyloxy)acetaldehyde(cas: 60656-87-3) is a non-natural aldehyde. It undergoes enantioselective Mukaiyama aldol reaction with silylketene acetal nucleophiles in the presence of C2-symmetric bis(oxazolinyl)pyridine Cu(II) complex (catalyst).Electric Literature of C9H10O2
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Ether | (C2H5)2O – PubChem