Sarhan, Alaadin E.’s team published research in Pharma Chemica in 2020 | CAS: 4637-24-5

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Synthetic Route of C5H13NO2

Synthetic Route of C5H13NO2In 2020 ,《New facile method for synthesis of 5-[(dimethylamino)methylene]pyrimidine-2,4,6-trione as potential template for barbiturate drugs》 appeared in Pharma Chemica. The author of the article were Sarhan, Alaadin E.. The article conveys some information:

New eco-friendly rapid synthesis of 5-[(dimethylamino)methylene]pyrimidine-2,4,6-trione was achieved by new method with efficient yield as potential template in synthesis of many biol. important organic compounds In the experiment, the researchers used many compounds, for example, N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5Synthetic Route of C5H13NO2)

N,N-Dimethylformamide Dimethyl Acetal(cas: 4637-24-5) belongs to anime. Primary amines having a tertiary alkyl group (R3CNH2) are difficult to prepare with most methods but are made industrially by the Ritter reaction. In this method a tertiary alcohol reacts with hydrogen cyanide (HCN) in the presence of a concentrated strong acid; a formamide, RNH―CHO, is formed first, which then undergoes hydrolysis.Synthetic Route of C5H13NO2

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem