Synthesis of Bicyclo[n.1.0]alkanes by a Cobalt-Catalyzed Multiple C(sp3)-H Activation Strategy was written by Zhang, Zhuo-Zhuo;Han, Ye-Qiang;Zhan, Bei-Bei;Wang, Sai;Shi, Bing-Feng. And the article was included in Angewandte Chemie, International Edition in 2017.COA of Formula: C9H10O4 This article mentions the following:
A Co-catalyzed dual C(sp3)-H activation strategy was developed and it provides a novel strategy for the synthesis of bicyclo[4.1.0]heptanes and bicyclo[3.1.0]hexanes. A key to the success of this reaction is the conformation-induced methylene C(sp3)-H activation of the resulting cobaltabicyclo[4.n.1] intermediate. The synthesis of bicyclo[3.1.0]hexane from pivalamide, by a triple C(sp3)-H activation, also was demonstrated. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7COA of Formula: C9H10O4).
2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.COA of Formula: C9H10O4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem