Synthesis of 4-nitro- and 4-aminophenylazacrown ethers was written by Oshchepkov, Aleksandr S.;Oshchepkov, Maksim S.;Anisimov, Alexander V.;Fedorova, Olga A.. And the article was included in Makrogeterotsikly in 2015.HPLC of Formula: 66943-05-3 This article mentions the following:
The study was dedicated to finding optimal reaction conditions for the introduction of 4-nitro- and 4-aminophenyl substituents into the structure of azacrown ethers with a varied ratio of oxygen to nitrogen heteroatoms. The synthetic procedure was proposed for the synthesis of 4-nitroaryl derivatives of crown ethers. This method was remarkably simple, has easy work-up and affords the formation solely of the monoarylation product. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3HPLC of Formula: 66943-05-3).
1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.HPLC of Formula: 66943-05-3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem