One-pot preparation of arylalkynes by a tandem catalytic iodination of arenes and palladium-catalyzed coupling of iodoarenes with terminal alkynes was written by Wan, Shun;Wang, Sunewang R.;Lu, Wenjun. And the article was included in Journal of Organic Chemistry in 2006.Category: ethers-buliding-blocks This article mentions the following:
Iodination of activated arenes by air-oxidation was carried out in the presence of catalytic bismuth salts at room temperature Subsequently, the formed iodoarenes reacted with terminal alkynes to give arylalkynes under a selected palladium-catalyzed coupling condition in the same pot. In the experiment, the researchers used many compounds, for example, 4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2Category: ethers-buliding-blocks).
4-Iodo-1-methoxy-2-methylbenzene (cas: 75581-11-2) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. But ether is more polar than alkenes. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Category: ethers-buliding-blocks
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem