Quantitative structure-activity relationship (QSAR) studies on the inhibition of porcine pancreatic amylase by cinnamic acid derivatives was written by Ramanan, P. N.;Kutty, A. V. Moiden;Rao, M. N. A.. And the article was included in Indian Journal of Biochemistry & Biophysics in 1987.Recommanded Product: 6972-61-8 This article mentions the following:
The inhibition of porcine pancreatic α-amylase by cinnamic acid derivatives with various substitutions on the Ph ring was studied. Quant. correlation by regression anal. showed that hydrophobicity of the substituents was important for the inhibitory activity. Ionization studies showed that all of the compounds were present in highly ionized form at pH 7.4. In the experiment, the researchers used many compounds, for example, 3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8Recommanded Product: 6972-61-8).
3-(2,4-Dimethoxyphenyl)acrylic acid (cas: 6972-61-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Recommanded Product: 6972-61-8
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem