A novel and direct synthesis of chroman derivatives using a hypervalent iodine(III) reagent was written by Hamamoto, Hiromi;Hata, Kayoko;Nambu, Hisanori;Shiozaki, Yukiko;Tohma, Hirofumi;Kita, Yasuyuki. And the article was included in Tetrahedron Letters in 2004.SDS of cas: 3929-47-3 This article mentions the following:
The direct aromatic carbon-oxygen bond-formation reaction was described and the novel and simple synthetic method for chroman derivatives involving aromatic cation radical intermediates was developed using the hypervalent iodine(III) reagent, phenyliodine(III) bis(trifluoroacetate) (PIFA). In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3SDS of cas: 3929-47-3).
3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.SDS of cas: 3929-47-3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem