Gu, Xue Ping et al. published their research in Journal of Organic Chemistry in 1986 | CAS: 60221-37-6

2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Safety of 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol

2-Chloro-1-(chloromethyl)ethyl methoxymethyl ether as a reagent for acetonylation of alcohols and phenol was written by Gu, Xue Ping;Ikeda, Isao;Komada, Satoru;Masuyama, Araki;Okahara, Mitsuo. And the article was included in Journal of Organic Chemistry in 1986.Safety of 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol This article mentions the following:

Treatment of ROH [R = decyl, cyclohexyl, Ph, Me3C, Me(CH2)9OCH2(CH2OCH2)3CH2OH, etc.] with ClCH2CH(CH2Cl)OCH2OMe (I), Bu4N+ HSO4–, and a base (e.g., NaOH) gave ROCH2C(:CH2)OCH2OMe, which were treated with aqueous H2SO4 to give 42-83% ROCH2COMe. Similar treatment of HOCH2(CH2OCH2)2CH2OH with I, but without Bu4N+ HSO4–, gave 61% MeCOCH2OCH2(CH2OCH2)2CH2OCH2COMe. In the experiment, the researchers used many compounds, for example, 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6Safety of 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol).

2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol (cas: 60221-37-6) belongs to ethers. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Safety of 2-(2-(2-((Tetrahydro-2H-pyran-2-yl)oxy)ethoxy)ethoxy)ethan-1-ol

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem