Ozcan, Elif et al. published their research in ChemistrySelect in 2021 | CAS: 111-77-3

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Synthetic Route of C5H12O3

Effect of the Hydrophilic/Hydrophobic Pendants on Physicochemical Properties: Applications Based on Cyclotriphosphazene Core was written by Ozcan, Elif;Uslu, Aylin. And the article was included in ChemistrySelect in 2021.Synthetic Route of C5H12O3 This article mentions the following:

This study focused on investigating the effect of hydrophilic and hydrophobic substituents on the physicochem. properties for medical applications. In this study, to understand the effect of hydrophilic and hydrophobic substituents on physicochem. parameters such as lipophilicity and thermosensitivity, a series of cis-tris nongeminal [N3P3(R1-4)3(Ra-f)3] cyclotriphosphazenes [R1-4=diethylene glycol monomethyl ether (DEGME), triethylene glycol monomethyl ether (TEGME), methoxypolyethylene glycol (mPEG350), methoxypolyethylene glycol-550 (mPEG550); (2-5) resp.; Ra-f=pyrazole, 3,5-dimethylpyrazole, imidazole, 2-Me imidazole, benzimidazole, 5,6-di-Me benzimidazole, [2(a-f), 3(a-f), 4(a-f), 5(a-f)] resp.] were synthesized and fully characterized by mass, 31P and 1H NMR spectroscopies. Solubility and thermosensitivity based on substituent dependent LCST (lower critical solution temperature) behavior of all synthesized mols. are investigated. Each compound analyzed by HPLC to determine the lipophilicity values (logPo/w) between n-octanol and water. A good correlation (r = 0.9975 and R2 = 0.9948) was observed between the exptl. determined logPo/w and estimated milogP values. The results showed that LCST values of the reported compounds were linearly correlated with their lipophilicity values. In the experiment, the researchers used many compounds, for example, 2-(2-Methoxyethoxy)ethanol (cas: 111-77-3Synthetic Route of C5H12O3).

2-(2-Methoxyethoxy)ethanol (cas: 111-77-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Synthetic Route of C5H12O3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem