Synthesis of actinomycin D analogs: XXIII. Actinocin derivatives containing azacrown fragments was written by Ovchinnikov, D. V.;Glibin, E. N.;Garabadzhiu, A. V.;Plekhanova, N. G.. And the article was included in Russian Journal of General Chemistry in 2010.Electric Literature of C10H21NO4 This article mentions the following:
A number of actinocin amides containing residues of aza-15-crown-5 and aza-18-crown-6 where crown fragments, e.g. I, were separated from the heterocyclic chromophore by the residues of ω-amino acids were obtained as actinomycin D models. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Electric Literature of C10H21NO4).
1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. At room temperature, ethers are pleasant-smelling colourless liquids. Relative to alcohols, ethers are generally less dense, are less soluble in water, and have lower boiling points. They are relatively unreactive, and as a result they are useful as solvents for fats, oils, waxes, perfumes, resins, dyes, gums, and hydrocarbons. Vapours of certain ethers are used as insecticides, miticides, and fumigants for soil.Electric Literature of C10H21NO4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem