Recyclable Copper Catalyst for meta-Selective carbon-hydrogen bond arylation was written by Lee, Eun-Young;Park, Jai-Wook. And the article was included in ChemCatChem in 2011.Application of 56619-93-3 This article mentions the following:
A heterogeneous copper catalyst which is composed of metal nanoparticles entrapped in aluminum (oxy)hydroxide nanofibers [i.e., copper nanoparticles supported on aluminum hydroxide oxide AlO(OH) nanofibers] was recently reported. Using the above-mentioned supported recyclable catalyst (green chem. method) the synthesis of the target compounds was achieved by a reaction of diphenyliodonium triflate with anilide derivatives and furthermore, a phenylation of 1-(2,3-dihydro-1H-indol-1-yl)-2,2-dimethyl-1-propanone gave 1-(2,3-dihydro-6-phenyl-1H-indol-1-yl)-2,2-dimethyl-1-propanone. In the experiment, the researchers used many compounds, for example, N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3Application of 56619-93-3).
N-(3-Methoxyphenyl)pivalamide (cas: 56619-93-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. The unique properties of ethers (i.e., that they are strongly polar, with nonbonding electron pairs but no hydroxyl group) enhance the formation and use of many reagents. For example, Grignard reagents cannot form unless an ether is present to share its lone pair of electrons with the magnesium atom. Complexation of the magnesium atom stabilizes the Grignard reagent and helps to keep it in solution.Application of 56619-93-3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem