Organophotoredox-catalyzed cyanoalkylation of 1,4-quinones was written by Kulthe, Arun D.;Jaiswal, Sunidhi;Golagani, Durga;Mainkar, Prathama S.;Akondi, Srirama Murthy. And the article was included in Organic & Biomolecular Chemistry in 2022.Quality Control of 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione This article mentions the following:
A visible-light-induced metal-free cyanoalkylation of 1,4-quinones under mild and redox-neutral conditions to afford desired cyanoalkylated quinones I [R = H, Ph, Bn, etc.; R1 = H, Me, OH, etc.; X = CHR2, CH2, O; R2 = 4-t-BuPh, Bu, etc.] was described. This reaction proceeded at room temperature without the need of extra base or additive and was suitable for a variety of 1,4-quinones and differently substituted cyclobutanone oxime esters. Further transformation of cyano functionality to tetrazole and amine had also been demonstrated to showcase the advantage of this method to prepare drug-like mols. In the experiment, the researchers used many compounds, for example, 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7Quality Control of 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione).
2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione (cas: 605-94-7) belongs to ethers. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides. Autoxidation is the spontaneous oxidation of a compound in air. In the presence of oxygen, ethers slowly autoxidize to form hydroperoxides and dialkyl peroxides. If concentrated or heated, these peroxides may explode. To prevent such explosions, ethers should be obtained in small quantities, kept in tightly sealed containers, and used promptly.Quality Control of 2,3-Dimethoxy-5-methylcyclohexa-2,5-diene-1,4-dione
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem