Ji, Renjie et al. published their research in Macromolecules (Washington, DC, United States) in 2010 | CAS: 66943-05-3

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Application of 66943-05-3

Protonated Amino Acid-Induced One-Handed Helicity of Polynorbornene Having Monoaza-18-crown-6 Pendants was written by Ji, Renjie;Chao, Chih-Gang;Huang, Yen-Chin;Lan, Yi-kang;Lu, Cheng-Lu;Luh, Tien-Yau. And the article was included in Macromolecules (Washington, DC, United States) in 2010.Application of 66943-05-3 This article mentions the following:

Upon complexation with protonated amino acids, one-handed helical polynorbornenes appended with monoaza-18-crown-6 (I) are obtained. The cooperativity is observed as revealed by the sergeant-soldier effect and the majority rule. When sterically hindered amino acids such as phenylalanine, isovaline or proline, esters of amino acids, and aminoalcs. are used, the Δε values in CD spectra are significantly reduced. The protonated ammonium ion may form complex with a crown ether moiety whereas the carboxylic acid may form hydrogen bonding with the adjacent crown ether pendant resulting in unidirectional orientation of the pendants leading to a helical scaffold. The corresponding dimer with the same isotactic stereochem. as that of polynorbornene I behaves similarly to exhibit bisignate CD curve upon treatment with protonated alanine. Polynorbornene with monoaza-15-crown-5 does not exhibit any CD response under the same conditions. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Application of 66943-05-3).

1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Application of 66943-05-3

Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem