Month: December 2022

Gao, Hui published the artcileElectrochemical benzylic C-H arylation of xanthenes and thioxanthenes without a catalyst and oxidant, Formula: C8H10O2, the publication is Organic Chemistry Frontiers (2022), 9(7), 1911-1916, database is CAplus.

A catalyst-free and oxidant-free C-H arylation of xanthenes and thioxanthenes I (R¹ = H, Me, OH, Cl, etc.; R² = H, OMe; R³R⁴ = -CH=CH-CH=CH-; X = O, S) using electrochem. has been developed, which affords a number of cross-coupling products II (R⁵ = 4-methoxyphenyl, 4-methoxy-3-methylphenyl, 4-methoxy-3,5-dimethylphenyl, 2H-1,3-benzodioxol-5-yl, etc.) in moderate to good yields. This method is atom- and step-economical as it uses cheap and easily available arenes and heteroarenes as partners directly and the C(sp²)-H/C(sp³)-H type cross-coupling reaction.

Organic Chemistry Frontiers published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Formula: C8H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Jia-Qin published the artcileBromination of phenyl ether and other aromatics with bromoisobutyrate and dimethyl sulfoxide, Recommanded Product: 2-Methoxynaphthalene, the publication is Tetrahedron Letters (2021), 153375, database is CAplus.

Bromoisobutyrate was used for the first time as a general brominating source for the direct bromination of a diverse of simple Ph ethers. Aromatic ethers bearing various substituents was compatible in this reaction system delivered brominated arenes ArOMe [Ar = 4-Br-2,3-diMeC₆H₂, 4-NHAc-3-Br-C₆H₃, 1-Br-2-naphthyl, etc.] in moderate to good yields. The reaction system was expanded to bromination of phenols and unactivated arene. This process was regarded as an alternative for the well-established bromination systems for bromoarene synthesis.

Tetrahedron Letters published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C11H10O, Recommanded Product: 2-Methoxynaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Chengxi published the artcileEfficient Synthesis of Sterically Hindered Arenes Bearing Acyclic Secondary Alkyl Groups by Suzuki-Miyaura Cross-Couplings, Application In Synthesis of 2944-47-0, the publication is Angewandte Chemie, International Edition (2015), 54(12), 3792-3796, database is CAplus and MEDLINE.

Bulky P,P:O ligands I (R = H, OMe, NMe₂) were designed and synthesized to inhibit isomerization and reduction side reactions during the cross coupling between sterically hindered aryl halides and alkylboronic acids. Suzuki-Miyaura cross-couplings between di-ortho-substituted aryl bromides and acyclic secondary alkylboronic acids using one of these ligands were achieved with high yields. The method also enabled the preparation of ortho-alkoxy/di-ortho-substituted arenes bearing iso-Pr groups in excellent yields. The utility of the synthetic method was demonstrated in a late-stage modification of estrone and in the application to a new synthetic route towards gossypol.

Angewandte Chemie, International Edition published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Application In Synthesis of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Sun, Kangkang published the artcileCobalt Nanoparticles Embedded in N-Doped Porous Carbon Derived from Bimetallic Zeolitic Imidazolate Frameworks for One-Pot Selective Oxidative Depolymerization of Lignin, Category: ethers-buliding-blocks, the publication is ChemCatChem (2019), 11(4), 1264-1271, database is CAplus.

Co nanoparticles embedded in N-doped porous C (Co@CN) were prepared by the pyrolysis of bimetallic zeolitic imidazolate frameworks (BMZIFs) based on ZIF-8 and ZIF-67. The catalyst shows excellent catalytic efficiency in 1-pot selective oxidative cleavage of different linkages like β-O-4, α-O-4 and β-1 in organosolv lignin and lignin model compounds in the presence of O (ambient pressure) under mild conditions (383 K). Compared with traditional supported catalyst, the catalyst gives a highly hollow structure, which favored the adsorption of substrates and O. The uniform Co nanoparticles surrounded by N-doped graphitic structures and the strong electron transfer from graphitic N to Co NPs make it hard to be oxidized prior to use and higher catalytic reactivity. Also, the catalyst can be easily recovered by magnetic force after the reaction, and reused after reduction for 5 times without an obvious change in yields.

ChemCatChem published new progress about 183303-74-4. 183303-74-4 belongs to ethers-buliding-blocks, auxiliary class Benzene,Alcohol,Ether, name is 1-(3,4-Dimethoxyphenyl)-2-phenoxyethanol, and the molecular formula is C27H29N5O5, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Peng, Kang-Yung published the artcileEfficient Light Harvesting by Sequential Energy Transfer across Aggregates in Polymers of Finite Conjugational Segments with Short Aliphatic Linkages, SDS of cas: 146370-51-6, the publication is Journal of the American Chemical Society (2001), 123(46), 11388-11397, database is CAplus and MEDLINE.

A series of light-harvesting polymers (poly-DSBs) of dialkyloxy- or dialkyl-substituted distyrylbenzene ( substituents = methoxy, 2-ethylhexyloxy, and cyclohexyl) with methylene or ethylene spacers were prepared The interactions between lumophores and the role of chem. structure of poly-DSBs on the absorption, emission, and excitation spectra were studied. The proximity of distyrylbenzene lumophores was critical to effective interactions and to the energy-transfer processes. In concentrated solutions and solid films, intermol. aggregates exist resulting from different extents of interactions between lumophores and involve at least three species: loose, compact, and aligned aggregates as observed by photoluminescence and excitation spectroscopy. Sequential energy transfer was directly observed from individual lumophores to the most compact, aligned aggregates via looser intermol. aggregates by time-resolved fluorescence spectroscopy. This process mimics energy transfer in photosynthesis and is highly efficient; fluorescence can be red-shifted drastically by the presence of comparatively few aggregates and light from concentrated solutions and films of poly-DSBs is entirely or almost due to aggregation emission. Although sequential energy-transfer in fully conjugated electro/photoluminescent polymers due to inhomogeneity other than distributed conjugation length has never been directly observed at room temperature, events similar to those observed in poly-DSBs could occur but on a much shorter time scale, i.e., a few picoseconds.

Journal of the American Chemical Society published new progress about 146370-51-6. 146370-51-6 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 1-((2-Ethylhexyl)oxy)-4-methoxybenzene, and the molecular formula is C15H24O2, SDS of cas: 146370-51-6.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

An, Ran published the artcileSynthesis of propylene glycol methyl ether catalyzed by imidazole polymer catalyst: Performance evaluation, kinetics study, and process simulation, Related Products of ethers-buliding-blocks, the publication is Chemical Engineering Journal (Amsterdam, Netherlands) (2021), 126636, database is CAplus.

An imidazole polymer (divinylbenzene-vinylimidazole) catalyst (P-DVB-VIM) was developed for production of the eco-friendly solvent propylene glycol Me ether (PGME) by the propoxylation reaction of propylene oxide (PO) with methanol (ME). The catalyst was characterized in detail by SEM, Fourier-transform IR spectroscopy (FTIR), and Brunauer-Emmett-Teller (BET) anal. ¹H NMR was used to characterize the structural features of the catalyst precursor, i.e., the linear polymer of vinylimidazole (PVIM). An “electrophile nucleophile dual activation” ring-opening mechanism was proposed based on the “cooperative effect” of the reactant and PVIM. The catalytic performance was investigated and optimized at 100-130°C using an autoclave batch reactor. The results reveal that the P-DVB-VIM shows excellent catalytic performance, exhibiting the highest turnover frequency (TOF) number at 120°C within 45 min. The reaction kinetics was systematically studied using the pseudohomogeneous (PH) kinetic model. The kinetic parameters were determined by non-linear regression anal. of the exptl. data. Validation of the model showed that the exptl. data were in good agreement with the predicted outcomes. Moreover, based on the proposed kinetic model, steady-state simulations of the production of PGME in a fixed-bed reactor were carried out to determine the optimal design parameters, thus providing a useful guide for the design and production of PGME on the industrial scale.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zhang, Hai-Jun published the artcileChemoselective, Scalable Nickel-Electrocatalytic O-Arylation of Alcohols, Computed Properties of 959972-40-8, the publication is Angewandte Chemie, International Edition (2021), 60(38), 20700-20705, database is CAplus and MEDLINE.

Herein a Ni-catalyzed electrochem. driven protocol to afford aryl-alkyl ether bonds through O-arylation of alcs. was depicted. This electrochem. method did not require strong base, exogenous expensive transition metal catalysts (e.g., Ir, Ru), and could easily be scaled up in either a batch or flow setting. Interestingly, e-etherification exhibited an enhanced substrate scope over the mechanistically related photochem. variant as it tolerated tertiary amine functional groups in the alc. nucleophile. with a broad substrate scope in an operationally simple way.

Angewandte Chemie, International Edition published new progress about 959972-40-8. 959972-40-8 belongs to ethers-buliding-blocks, auxiliary class Boronic acid and ester,Benzene,Ether,Boronate Esters,Boronic Acids,Boronic acid and ester, name is 2-(4-(2-Methoxyethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C21H24O8, Computed Properties of 959972-40-8.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Han, Xiaocui published the artcileNovel Polymers with Ultrapermeability Based on Alternately Planar and Contorted Units for Gas Separation, Name: 1,2-Dimethoxybenzene, the publication is ACS Materials Letters (2022), 4(1), 61-67, database is CAplus.

Polymers of intrinsic microporosity (PIMs) have been the potential candidates as gas separation membrane materials, because of their high permeability and good processing. Here, three PIMs (PIM-ABAs) with ultrahigh permeability are reported; these are significantly more permeable than the PIM-1 and other PIMs reported and do not lose high selectivity and good processing merit. The introduction of large and rigid planar units alternatively contorted units suppresses the compact packing of polymer chains, resulting in the hierarchical porosity range of 0.5-4.0 nm. The presence of larger pores is responsible for promoting permeability. PIM-ABA-OMEN demonstrates the optimal CO₂ permeability (16 736 barrer), which is 3.95 times more than PIM-1 (4234 barrer) with equivalent gas selectivity and PIM-ABA-EN exhibits the promotion of both permeability and selectivity. After being aged for 186 days, PIM-ABAs still showed the CO₂ permeability above 8000 barrer, which is almost as 2 times greater than that of unaged PIM-1. This work provides a new strategy for the preparation of PIMs with enhanced gas separation performance.

ACS Materials Letters published new progress about 91-16-7. 91-16-7 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether,Inhibitor,Inhibitor,Inhibitor, name is 1,2-Dimethoxybenzene, and the molecular formula is C8H10O2, Name: 1,2-Dimethoxybenzene.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Zeng, Bo published the artcileNitrogen-doped cobalt nanocatalysts for carbonylation of propylene oxide, Product Details of C4H10O2, the publication is Molecular Catalysis (2020), 111109, database is CAplus.

Nitrogen-doped cobalt nanoparticles loaded on porous supports were developed for ring-opening carbonylation of propylene oxide. The catalysts were prepared by simply pyrolysis of Co(OAc)₂/phenanthroline and supports. As proved by XPS combined with XRD and TEM characterizations, a higher amount of available Co-N sites were responsible for promoting the carbonylative activity. The selectivity of carbonylated products reached 93%, which is comparable to previously reported cobalt carbonyl catalysts. The novel type of carbonylative catalyst also could be reused and revealed fine stability due to the continuous generation of active [Co(CO)₄]^– species during reaction.

Molecular Catalysis published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C22H23BO4, Product Details of C4H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Webster-Gardiner, Michael S. published the artcileCatalytic Synthesis of “Super” Linear Alkenyl Arenes Using an Easily Prepared Rh(I) Catalyst, Synthetic Route of 2944-47-0, the publication is Journal of the American Chemical Society (2017), 139(15), 5474-5480, database is CAplus and MEDLINE.

Linear alkyl benzenes (LAB) are global chems. that are produced by acid-catalyzed reactions that involve the formation of carbocationic intermediates. One outcome of the acid-based catalysis is that 1-phenylalkanes cannot be produced. Herein, it is reported that [Rh(μ-OAc)(η²-C₂H₄)₂]₂ catalyzes production of 1-Ph substituted alkene products via oxidative arene vinylation. Since C=C bonds can be used for many chem. transformations, the formation of unsaturated products provides a potential advantage over current processes that produce saturated alkyl arenes. Conditions that provide up to a 10:1 linear:branched ratio have been achieved, and catalytic turnovers >1470 have been demonstrated. In addition, electron-deficient and electron-rich substituted benzenes are successfully alkylated. The Rh catalysis provides ortho:meta:para selectivity that is opposite to traditional acid-based catalysis.

Journal of the American Chemical Society published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C5H5NO3S, Synthetic Route of 2944-47-0.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem