Month: December 2022

Sulimov, A. V. published the artcileStudying the influence of process parameters on a process of epoxidation of propylene in methanol in the presence of titanium silicalite extruded, Recommanded Product: 2-Methoxypropan-1-ol, the publication is Kataliz v Promyshlennosti (2015), 15(6), 21-25, database is CAplus.

To obtain quant. information on the influence of process parameters on the basic laws of liquid-phase epoxidation of propylene with an aqueous solution of hydrogen peroxide in the presence of an extruded titanium silicalite in methanol medium. The effect of solvent (13,7-19,1 mol / l), the initial ratio of propylene: hydrogen peroxide ((2/5): 1), temperature (30-60 °C) to yield the desired product – propylene oxide – and byproducts: 1,2-propylene glycol, 1-methoxy-2-propanol and 2-methoxy-1-propanol. Based on the patterns of recommendations on the conditions of synthesis of propylene oxide in a laboratory continuous.

Kataliz v Promyshlennosti published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4Br2N2O4S, Recommanded Product: 2-Methoxypropan-1-ol.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Doval, David Alonso published the artcilePlanarizable push-pull oligothiophenes: in search of the perfect twist, Application In Synthesis of 596819-12-4, the publication is Chemical Science (2014), 5(7), 2819-2825, database is CAplus.

The concept to couple fluorophore planarization and fluorophore polarization for the construction of innovative fluorescent membrane probes is elaborated comprehensively in the context of oligothiophenes. Increasing length with different degree of twist from ter- to quinquethiophenes results in increasing extinction coefficients, decreasing quantum yields and relatively minor red shifts. Quaterthiophenes show maximal Stokes shifts and are thus preserved to further elaborate on deplanarization. Increasing quaterthiophene deplanarization results in increasing blue shifts and decreasing quantum yields in solution, whereas planarization in solid-ordered lipid bilayer membranes gives the resp. red shifts with fluorescence recovery. An extensive screening reveals that intermediate global deplanarization with strong individual twists near the membrane interface are best. Weaker and stronger global twisting and strong individual twists deeper in the membrane are less convincing because planarization becomes either too easy or too difficult. The best probe reports decreasing membrane fluidity with a red shift of 44 nm and a fluorescence increase of almost 500%. These insights are important because they cover significant chem. space to help improving our understanding of chromophore twisting and promise bright perspectives with regard to biol. applications and refined probe design.

Chemical Science published new progress about 596819-12-4. 596819-12-4 belongs to ethers-buliding-blocks, auxiliary class Thiophene,Boronic acid and ester,Ether,Boronate Esters,Boronic acid and ester, name is 2-(5-Methoxythiophen-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C11H17BO3S, Application In Synthesis of 596819-12-4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Galkin, Maxim V. published the artcileMild and Robust Redox-Neutral Pd/C-Catalyzed Lignol β-O-4′ Bond Cleavage Through a Low-Energy-Barrier Pathway, Safety of 1-(3,4-Dimethoxyphenyl)-2-phenoxyethanol, the publication is ChemSusChem (2015), 8(13), 2187-2192, database is CAplus and MEDLINE.

A Pd/C catalyzed redox neutral C-O bond cleavage of 2-aryloxy-1-arylethanols has been developed. The reactions are carried out at 80 °C, in air, using a green solvent system to yield the aryl ketones in near quant. yields. Addition of catalytic amounts of a hydrogen source to the reaction mixture activates the catalyst to proceed through a low energy barrier pathway. Initial studies support a transfer hydrogenolysis reaction mechanism that proceeds through an initial dehydrogenation followed by an enol adsorption to Pd/C and a reductive C-O bond cleavage.

ChemSusChem published new progress about 183303-74-4. 183303-74-4 belongs to ethers-buliding-blocks, auxiliary class Benzene,Alcohol,Ether, name is 1-(3,4-Dimethoxyphenyl)-2-phenoxyethanol, and the molecular formula is C16H18O4, Safety of 1-(3,4-Dimethoxyphenyl)-2-phenoxyethanol.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Wurzler, Gleicielle Tozzi published the artcileIntegrating bio-oil and carbohydrate valorization on the fractionation of sugarcane bagasse via Organosolv process using Mo₂C-based catalysts, Name: 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is Fuel Processing Technology (2022), 107208, database is CAplus.

This work studied the fractionation of sugarcane bagasse via Organosolv treatment using isopropanol/water in the presence of Raney-Ni and molybdenum carbide catalysts (Bulk Mo₂C and Mo2C supported on activated carbon (AC) or Al₂O₃). The degree of delignification, the bio-oil and solid residue composition depended on the type of catalyst. A partial extraction of hemicellulose occurred followed by depolymerization, resulting in a product distribution that depended on the catalyst. Raney-Ni catalyst promoted the formation of diols and triols, while xylose, furfural, and furan were mainly produced by Mo₂C based-catalysts. The Organosolv treatment without catalyst and in the presence of bulk Mo₂C produced a bio-oil containing mainly 2,3-dihydrobenzofuran. Mo₂C/AC and Mo₂C/Al₂O₃ are promising catalysts for the fractionation of sugarcane bagasse that produced a bio-oil with higher yield to substituted methoxyphenols and a solid residue more easily hydrolyzed by cellulases, producing higher yield to glucose than Raney-Ni catalyst.

Fuel Processing Technology published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C7H7IN2O, Name: 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Rocha, Ines L. D. published the artcileSelective Separation of Vanillic Acid from Other Lignin-Derived Monomers Using Centrifugal Partition Chromatography: The Effect of pH, Safety of 4-Hydroxy-3,5-dimethoxybenzaldehyde, the publication is ACS Sustainable Chemistry & Engineering (2022), 10(15), 4913-4921, database is CAplus.

In this work, centrifugal partition chromatog. (CPC) assisted by a polyethylene glycol (PEG)/sodium polyacrylate (NaPA) aqueous biphasic system (ABS) was applied in the separation of five lignin-derived monomers (vanillin, vanillic acid, syringaldehyde, acetovanillone, and p-hydroxybenzaldehyde). The influence of the system pH (unbuffered, pH 5, and pH 12) and added electrolytes (inorganic salts or ionic liquids (ILs)) on the compound partition was initially evaluated. The obtained data revealed that ILs induced more adequate partition coefficients (K < 5) than inorganic salts (K > 5) to enable separation performance in CPC, while alk. conditions (pH 12) demonstrated a pos. impact on the partition of vanillic acid. CPC runs, with buffered ABS at pH 12, enabled a selective separation of vanillic acid from other lignin monomers. Under these conditions, a distinct interaction between the top (PEG-rich) and bottom (NaPA-rich) phases of the ABS with the double deprotonated form of vanillic acid is expected when compared to the remaining lignin monomers (single deprotonated). This is an impactful result that shows the pH to be a crucial factor in the separation of lignin monomer compounds by CPC, while only unbuffered systems have been previously studied in the literature. Finally, the recovery of vanillic acid up to 96% purity and further recycling of ABS phase-forming components were approached as a proof of concept through the combination of ultrafiltration and solid-phase extraction steps.

ACS Sustainable Chemistry & Engineering published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Safety of 4-Hydroxy-3,5-dimethoxybenzaldehyde.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Jakubska-Busse, Anna published the artcileWhy does an obligate autogamous orchid produce insect attractants in nectar – a case study on Epipactis albensis (Orchidaceae), Product Details of C9H10O4, the publication is BMC Plant Biology (2022), 22(1), 196, database is CAplus and MEDLINE.

The flowers of some species of orchids produce nectar as a reward for pollination, the process of transferring pollen from flower to flower. Epipactis albensis is an obligatory autogamous species, does not require the presence of insects for pollination, nevertheless, it has not lost the ability to produce nectar, the chem. composition of which we examined by gas chromatog.-mass spectrometry (GC-MS) method for identification of potential insect attractants. During five years of field research, we did not observe any true pollinating insects visiting the flowers of this species, only accidental insects as ants and aphids. As a result of our studies, we find that this self-pollinating orchid produces in nectar inter alia aliphatic saturated and unsaturated aldehydes such as nonanal (pelargonal) and 2-pentenal as well as aromatic ones (i.e., syringaldehyde, hyacinthin). The nectar is low in alkenes, which may explain the absence of pollinating insects. Moreover, vanillin and eugenol derivatives, well-known as important scent compounds were also identified, but the list of chem. compounds is much poorer compared with a closely related species, insect-pollinating E. helleborine. Autogamy is a reproductive mechanism employed by many flowering plants, including the orchid genus Epipactis, as an adaptation to growing in habitats where pollinating insects are rarely observed due to the lack of nectar-producing plants they feed on. The production of numerous chem. attractants by self-pollinated E. albensis confirms the evolutionary secondary process, i.e., transition from ancestral insect-pollinating species to obligatory autogamous.

BMC Plant Biology published new progress about 134-96-3. 134-96-3 belongs to ethers-buliding-blocks, auxiliary class Immunology/Inflammation,COX,Natural product, name is 4-Hydroxy-3,5-dimethoxybenzaldehyde, and the molecular formula is C9H10O4, Product Details of C9H10O4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Adamczyk-Wozniak, Agnieszka published the artcileHydrogen bonds in phenylboronic acids with polyoxaalkyl substituents at ortho-position, COA of Formula: C9H13BO4, the publication is Journal of Molecular Structure (2009), 920(1-3), 430-435, database is CAplus.

Phenylboronic acids with polyoxaalkyl substituents at ortho position were synthesized from the corresponding bromides. Structures in solid state, determined by single crystal x-ray diffraction, reveal the presence of inter- and intramol. hydrogen bonds. Presence of several oxygen atoms in oxaalkyl chains enables the formation of intramol. hydrogen bonds by B(OH)₂ group with different oxygen centers which lead to the formation of bifurcated hydrogen bonds. Investigated compounds were characterized by ¹H, ¹³C, ¹¹B and ¹⁷O NMR spectroscopy in solution Assignment of ¹H and ¹³C signals was made on the basis of HSQC and HMBC spectra. ¹⁷O NMR spectra show that in acetonitrile solution hydrogen bonds with solvent mols. are predominant.

Journal of Molecular Structure published new progress about 1122568-09-5. 1122568-09-5 belongs to ethers-buliding-blocks, auxiliary class Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic Acids,Boronic acid and ester, name is (2-(2-Methoxyethoxy)phenyl)boronic acid, and the molecular formula is C9H13BO4, COA of Formula: C9H13BO4.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Della Sala, Giorgio published the artcileTowards the biosynthesis of the aromatic products of the Mediterranean mollusc Scaphander lignarius: isolation and synthesis of analogues of lignarenones, Category: ethers-buliding-blocks, the publication is Tetrahedron (2007), 63(30), 7256-7263, database is CAplus.

Secondary metabolites of the Mediterranean mollusc Scaphander lignarius from different collection sites have been investigated, proving the constant presence of a number of minor metabolites correlated to the already known lignarenones. Complete characterization of the new metabolites has been supported by enantioselective synthesis. The data are consistent with the origin of this unique class of ω-phenyloctanoids from a common polyketide pathway.

Tetrahedron published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Burkholder, Timothy P. published the artcileDesign and synthesis of a novel series of [1-(4-hydroxy-benzyl)-1H-indol-5-yloxy]-acetic acid compounds as potent, selective, thyroid hormone receptor β agonists, Product Details of C10H14O, the publication is Bioorganic & Medicinal Chemistry Letters (2015), 25(7), 1377-1380, database is CAplus and MEDLINE.

The design, synthesis, and structure activity relationships for a series of indoles, e.g., I, as potent, selective, thyroid hormone receptor β (TRβ) agonists is described. Compounds with >50× binding selectivity for TRβ over TRα were generated and evaluation of compound I from this series in a model of dyslipidemia demonstrated pos. effects on plasma lipid endpoints in vivo.

Bioorganic & Medicinal Chemistry Letters published new progress about 2944-47-0. 2944-47-0 belongs to ethers-buliding-blocks, auxiliary class Benzene,Ether, name is 2-Isopropylanisole, and the molecular formula is C10H14O, Product Details of C10H14O.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem

Li, Ying published the artcileIsolation and characterization of a novel bacterium Pseudomonas aeruginosa for biofertilizer production from kitchen waste oil, Product Details of C4H10O2, the publication is RSC Advances (2018), 8(73), 41966-41975, database is CAplus and MEDLINE.

Kitchen waste oil is composed of long chain triglycerides (LCTs) that has high energy d. However, it is hard to be degraded by microbes, thereby leading to increasing levels of environmental pollution due to landfill disposition. In this study, we isolated and characterized a novel bacterium Pseudomonas aeruginosa PA-3 that could convert kitchen waste oil into biofertilizer. PA-3 could survive on trilaurin or kitchen waste oil as the sole carbon source, and 10 g L^-1 trilaurin or kitchen waste oil was completely consumed within 7 days. Interestingly, the degradation products of kitchen waste oil can be used as biofertilizer in promoting cabbage growth. The plant height, leaf area and stem diameter of cabbage plants were all increased with the addition of kitchen waste oil cultivation products into the soil. Kitchen waste oil degradation products were analyzed by gas chromatog. mass spectrometry (GC-MS), and short chain alcs. or fatty acids were observed to be the main products. To unravel the mechanism underlying the accelerated cabbage growth, bacterial diversity of the soil was investigated after using this biofertilizer. Results showed that agricultural probiotics accumulated with the addition of kitchen waste oil cultivation products. Finally, the whole genome of PA-3 was sequenced and analyzed, which showed the existence of a complete β-oxidation pathway in the genome of PA-3. To our knowledge, this is the first study on kitchen waste oil degradation and re-utilization by bacteria, which provides a new method for waste source re-utilization.

RSC Advances published new progress about 1589-47-5. 1589-47-5 belongs to ethers-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-Methoxypropan-1-ol, and the molecular formula is C4H10O2, Product Details of C4H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem