Synthesis of 2-aryloxymethylbenzimidazole-1-propionitrile derivatives under microwave irradiation was written by Wei, Tai-bao;Hua, Mao-tang;Li, Xin-lin;Zhang, You-ming. And the article was included in Xibei Shifan Daxue Xuebao, Ziran Kexueban in 2012.HPLC of Formula: 1877-75-4 This article mentions the following:
A series of new 2-aryloxymethylbenzimidazole-1-propionitrile derivatives were synthesized by aza-Michael addition under micro wave-irradiation and characterized by elemental anal., IR, 1HNMR and 13CNMR. The mol. structure of 4e was determined by single crystal X-ray diffraction. The cell packing diagram shows that the complex is self-assembled with 1-dimensional supramol. chain supported by H-bonds and π-π interactions. In the experiment, the researchers used many compounds, for example, 2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4HPLC of Formula: 1877-75-4).
2-(4-Methoxyphenoxy)acetic acid (cas: 1877-75-4) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.HPLC of Formula: 1877-75-4
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem