Aza steroids. II. Approaches to the 13-azaequilenin system was written by Schleigh, William R.;Catala, Adria;Popp, Frank D.. And the article was included in Journal of Heterocyclic Chemistry in 1965.HPLC of Formula: 3929-47-3 This article mentions the following:
The synthesis of N-[2-(1-naphthyl)ethyl] succinimide, N-[2-(1-naphthyl)ethyl]pyrrolidone, and the corresponding 3,4-dihydro compounds is described. The pyrrolidones have been converted into 11,12,16,17-tetrahydro-13-azacyclopenta[a]phenanthrene and 6,7,11,12,16,17 – hexahydro – 13 – azacyclopenta[a]phenanthrene. These 2 compounds were then converted to I and II. The former compound is a salt of (+)-3-deoxy-17-deoxo-13-azaequilenin. In the experiment, the researchers used many compounds, for example, 3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3HPLC of Formula: 3929-47-3).
3-(3,4-Dimethoxyphenyl)propan-1-ol (cas: 3929-47-3) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. Ethers feature bent C–O–C linkages. In dimethyl ether, the bond angle is 111° and C–O distances are 141 pm. The barrier to rotation about the C–O bonds is low. The bonding of oxygen in ethers, alcohols, and water is similar. In the language of valence bond theory, the hybridization at oxygen is sp3.HPLC of Formula: 3929-47-3
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem