Synthesis and crystal structure of erythromycin A 9-(1-iso-propoxycyclohexyl)oxime was written by Liang, Jian-Hua;Yao, Guo-Wei;Zhao, Xin-Qi. And the article was included in Youji Huaxue in 2003.Related Products of 1132-95-2 This article mentions the following:
E- and Z-isomers of erythromycin A 9-(1-iso-propoxycyclohexyl)oxime have been synthesized and characterized. The crystal structure of E-isomer was determined by X-ray single-crystal structure anal. The crystal belongs to orthorhombic system, P212121 space group with a = 2.3101(5) nm, b =2.3761(5) an, c =0.97066 (19) nm, V=5.3279(18) nm3, Z=4, μ = 0.088 mm-1, F(000) =2064, D1 = 1.176 g/cm3, R1 =0.0505, wR2 = 0.0775 for 6747 unique reflections. The torsion angles of its fourteen-member erythrolide clearly elucidated the origin of regioselectivity occurring at 6-hydroxy in the O-methylation of erythromycin A. In the experiment, the researchers used many compounds, for example, 1,1-Diisopropoxycyclohexane (cas: 1132-95-2Related Products of 1132-95-2).
1,1-Diisopropoxycyclohexane (cas: 1132-95-2) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethyl ether is an excellent solvent for extractions and for a wide variety of chemical reactions. It is also used as a volatile starting fluid for diesel engines and gasoline engines in cold weather. Dimethyl ether is used as a spray propellant and refrigerant. Methyl t-butyl ether (MTBE) is a gasoline additive that boosts the octane number and reduces the amount of nitrogen-oxide pollutants in the exhaust. The ethers of ethylene glycol are used as solvents and plasticizers.Related Products of 1132-95-2
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem