Influence of aza-15-crown-5 with nootropic activity on protein metabolism in various regions of rat brain and blood was written by Karaseva, T. L.;Zapenko, G. N.;Basok, S. S.;Kulygina, K. Yu.;Luk’yanenko, N. G.. And the article was included in Ukrainica Bioorganica Acta in 2010.Category: ethers-buliding-blocks This article mentions the following:
The influence of crown-ether (CE), possessing nootropic activity on the protein metabolism in various structures of mice brain and rats blood in comparison with piracetam were studied. It was found, that CE was able to increase the protein content, activate the synthesis of total protein and its fractions in different regions of brain. The distinct inclusion of 3H-leucine and 35S-methionine in total content of blood proteins were found. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Category: ethers-buliding-blocks).
1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. The oxygen atom in ethers are more electronegative than carbon, thus the hydrogens which are alpha to the ethers are more acidic than the simple hydrocarbons. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Category: ethers-buliding-blocks
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem