Synthesis of carbon-11-labeled 4-aryl-4H-chromenes as new PET agents for imaging of apoptosis in cancer was written by Gao, Mingzhang;Wang, Min;Miller, Kathy D.;Hutchins, Gary D.;Zheng, Qi-Huang. And the article was included in Applied Radiation and Isotopes in 2009.Recommanded Product: 57179-35-8 This article mentions the following:
Carbon-11-labeled 4-aryl-4H-chromenes, 4-(3-[11C]methoxy-5-methoxyphenyl)-, 4-(3-bromo-4-[11C]methoxy-5-methoxyphenyl)-, 4-(3-[11C]methoxy-5-methoxyphenyl)-, 4-(3-bromo-4-[11C]methoxy-5-methoxyphenyl)-, 4-(3-[11C]methoxy-5-methoxyphenyl)-, 4-(3-bromo-4-[11C]methoxy-5-methoxyphenyl)-, 4-(3-[11C]methoxy-5-methoxyphenyl)- and 4-(3-bromo-4-[11C]methoxy-5-methoxyphenyl)–2-amino-7-methyl-4,7-dihydropyrano[2,3-e]indole-3-carbonitrile were prepared by O-[11C]methylation of their alc. precursors using [11C]CH3OTf under basic conditions and isolated by a simplified solid-phase extraction (SPE) method in 30-50% radiochem. yields based on [11C]CO2 and decay corrected to end of bombardment (EOB). The overall synthesis time from EOB was 15-20 min, the radiochem. purity was >99%, and the specific activity at end of synthesis (EOS) was 111-185 GBq/μmol. In the experiment, the researchers used many compounds, for example, 3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8Recommanded Product: 57179-35-8).
3-Hydroxy-5-methoxybenzaldehyde (cas: 57179-35-8) belongs to ethers. Of all the functional groups, ethers are the least reactive ones. Ether bonds are quite stable towards bases, oxidizing agents and reducing agents. But on the other hand, ethers undergo cleavage by reaction with acids. Ethers can form hydrogen bonds with other molecules (alcohols, amines, etc.) that have O―H or N―H bonds. The ability to form hydrogen bonds with other compounds makes ethers particularly good solvents for a wide variety of organic compounds and a surprisingly large number of inorganic compounds.Recommanded Product: 57179-35-8
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem