Synthesis of tethered bis-macrocycles by cross-coupling of N-(3,5-dibromobenzyl)azacrowns with α,ω-diamino compounds was written by Anokhin, Maksim V.;Averin, Alexei D.;Buryak, Alexei K.;Beletskaya, Irina P.. And the article was included in Mendeleev Communications in 2011.Name: 1,4,7,10-Tetraoxa-13-azacyclopentadecane This article mentions the following:
Palladium-catalyzed cross-coupling of N-(3,5-dibromobenzyl) derivatives of 1-aza-15-crown-5 and 1-aza-18-crown-6 with a,w-diamino compounds afforded macrocyclization products comprising two tethered different azacrowns. In the experiment, the researchers used many compounds, for example, 1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3Name: 1,4,7,10-Tetraoxa-13-azacyclopentadecane).
1,4,7,10-Tetraoxa-13-azacyclopentadecane (cas: 66943-05-3) belongs to ethers. Ether is less polar than esters, alcohols or amines because of the oxygen atom that is unable to participate in hydrogen bonding due to the presence of bulky alkyl groups on both sides of the oxygen atom. Ethers are good solvents partly because they are not very reactive. Most ethers can be cleaved, however, by hydrobromic acid (HBr) to give alkyl bromides or by hydroiodic acid (HI) to give alkyl iodides.Name: 1,4,7,10-Tetraoxa-13-azacyclopentadecane
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem