Rausaria, Smita published the artcileManganese(III) Complexes of Bis(hydroxyphenyl)dipyrromethenes Are Potent Orally Active Peroxynitrite Scavengers, SDS of cas: 127972-00-3, the main research area is manganese chelate biscyclohexano fused bishydroxyphenyldipyrromethene preparation crystal structure; oral analgesic activity manganese chelate biscyclohexano fused bishydroxyphenyldipyrromethene; peroxynitrite scavenger manganese chelate biscyclohexano fused bishydroxyphenyldipyrromethene.
The authors report biscyclohexano-fused Mn(III) complexes of bis(hydroxyphenyl)dipyrromethenes, complexes I (R1 = H, Me, or F, 4a-c, resp.,) as potent and orally active peroxynitrite scavengers. Complexes 4a-c reduce peroxynitrite through a two-electron mechanism, thereby forming the corresponding Mn(V)O species, which were characterized by UV, NMR, and LC-MS methods. Mn(III) complex 4b and its strained boron (BODIPY) analog 9b were analyzed by x-ray crystallog. Finally, complex 4a is an orally active and potent analgesic in a model carrageenan-induced hyperalgesia known to be driven by the over-production of peroxynitrite.
Journal of the American Chemical Society published new progress about Analgesics. 127972-00-3 belongs to class ethers-buliding-blocks, name is 2-Methoxy-5-methylphenylboronic acid, and the molecular formula is C8H11BO3, SDS of cas: 127972-00-3.
Referemce:
Ether – Wikipedia,
Ether | (C2H5)2O – PubChem