Muller, Norbert published the artcileFluorine chemical shifts and microheterogeneity in aqueous solutions of 2-(2,2,2-trifluoroethoxy)ethanol, Category: ethers-buliding-blocks, the publication is Journal of Physical Chemistry (1979), 83(15), 2041-4, database is CAplus.
The title compound was prepared in the expectation that its water solutions would show interesting structural effects similar to those suggested by a variety of measurements for aqueous tert-Bu alc. and aqueous 2-n-butoxyethanol and that the nature of these effects might be elucidated by following the fluorine chem. shift as a function of concentration and temperature The material is miscible with water above room temperature, but an upper critical solution temperature was found between 1 and 2°. Chem. shift-composition curves determined at five temperatures spanning the interval from 1 to 61° reveal a change in the nature of the solutions when the mole fraction of the nonaqueous component is about 0.18. It appears that in the dilute region the cosolvent mols. are preferentially solvated by water, especially at the lower temperatures, while the more concentrated solutions are microheterogeneous, with rapid exchange of the organic species between water-rich and cosolvent-rich domains. It is very likely that the properties of aqueous solutions of tert-Bu alc., 2-n-butoxyethanol, and 2-(2,2,2-trifluoroethoxy)ethanol indeed reflect essentially the same type of behavior.
Journal of Physical Chemistry published new progress about 2358-54-5. 2358-54-5 belongs to ethers-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Aliphatic hydrocarbon chain,Alcohol,Ether, name is 2-(2,2,2-Trifluoroethoxy)ethanol, and the molecular formula is C4H7F3O2, Category: ethers-buliding-blocks.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem