Zhang, Hongliang’s team published research in Organic Chemistry Frontiers in 9 | CAS: 93-04-9

Organic Chemistry Frontiers published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C15H24S, Related Products of ethers-buliding-blocks.

Zhang, Hongliang published the artcileElectrophilic amidomethylation of arenes with DMSO/MeCN reagents, Related Products of ethers-buliding-blocks, the publication is Organic Chemistry Frontiers (2022), 9(9), 2430-2437, database is CAplus.

An efficient electrophilic amidomethylation of aromatics was described to construct N-benzylic amides, which are core structures in drugs and natural products. The simple combination of DMSO (DMSO, as the CH2 unit) and acetonitrile (MeCN, as the nitrogen unit) as a highly active amidomethylation reagent enables the efficient C-C, C-N and C=O bond construction. Notably, this method provides a practical protocol for the efficient preparation of deuterated benzylamine derivatives with easily available d6-DMSO or d3-MeCN, and is also applied in the concise synthesis of Nonivamide and Pimavanserin.

Organic Chemistry Frontiers published new progress about 93-04-9. 93-04-9 belongs to ethers-buliding-blocks, auxiliary class Naphthalene,Ether, name is 2-Methoxynaphthalene, and the molecular formula is C15H24S, Related Products of ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem