Pilania, Meenakshi published the artcileCu-Catalyzed Expeditious Synthesis of N-Benzylaminoheterocycles Using N-Tosylhydrazones and Aminoheteroarenes, Quality Control of 52818-63-0, the publication is ChemistrySelect (2016), 1(20), 6368-6373, database is CAplus.
N-Tosylhydrazones were successfully coupled in the presence of CuI (10 mol%) with various heterocyclic amines to develop a convenient and high yielding protocol for the preparation of N-benzylaminoheterocycles under microwave irradiation This ligand-free new methodol. used readily available starting materials and a cheaper copper catalyst. A wide range of O, N and S containing heteroarylamines and o-phenylenediamine were explored to prepare N-benzylaminoheterocycles and 1,2-disubstituted benzimidazoles. The protocol was equally effective with N-tosylhydrazones derived from aldehydes and ketones, especially ferrocene aldehyde to prepare an array of N-benzylaminoheterocycles in good to excellent yields. Finally, the identified reaction conditions were utilized to prepare drug-like mols. namely pyrido[1,2-a]benzimidazole and N-substituted-2-amino-thiazole derivative as antitubercular agents.
ChemistrySelect published new progress about 52818-63-0. 52818-63-0 belongs to ethers-buliding-blocks, auxiliary class Pyridine,Amine,Benzene,Ether, name is N-(4-Methoxybenzyl)pyridin-2-amine, and the molecular formula is C13H14N2O, Quality Control of 52818-63-0.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem