Liu, Zhuqing’s team published research in Organic Letters in 24 | CAS: 6850-57-3

Organic Letters published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Category: ethers-buliding-blocks.

Liu, Zhuqing published the artcilePhIO-Mediated Oxidative C=C Bond Cleavage and Reassembly toward Highly Functionalized Oxazolones, Category: ethers-buliding-blocks, the publication is Organic Letters (2022), 24(6), 1323-1328, database is CAplus and MEDLINE.

An efficient PhIO-mediated oxidative C = C bond cleavage and reassembly of enaminone toward oxazolone I [R1 = Ph, 3-MeC6H4, 4-MeC6H4, etc.; R2 = Me, Et; R3 = Bn, 2-MeOC6H4, CH2CH2Ph, etc.] with high regioselectivity was reported. DFT calculations revealed that the reaction proceeded through oxygen atom transfer, C = C bond cleavage, alkylthio migration, and reassembly cascade. This strategy was highlighted by high atom and step economy with formation of five bonds in one pot and generation of high-valued oxazolone skeleton under mild conditions.

Organic Letters published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Category: ethers-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem