Liu, Chao published the artcileRapid construction of C4-substituted phenanthridinones through palladium-catalyzed domino N-arylation/aryl-aryl coupling process, Synthetic Route of 6850-57-3, the publication is Molecular Catalysis (2021), 111766, database is CAplus.
An excellent chemo- and regioselective palladium-catalyzed cascade intermol. N-arylation/aryl-aryl coupling process had been developed. Employing Pd(TFA)2, PCy3•HBF4, K2CO3 and 1,4-dioxane in an oil bath at 100°C for 12 h, diverse C4-substituted phenanthridinones I [R = H, Me, OMe; R1 = Me, Ph, 2-thienyl, etc.; R2 = H, Me, OMe, F] were synthesized from o-bromobenzamides in 42-92% yield. Broad substrate scope and excellent functional group tolerance were observed The synthetic utility of this method was illustrated by the further derivatization to prepare multiple-substituted phenanthridinones II [R3 = Et, Bn, 1-adamantyl] in 30-75% yield.
Molecular Catalysis published new progress about 6850-57-3. 6850-57-3 belongs to ethers-buliding-blocks, auxiliary class Amine,Benzene,Ether, name is (2-Methoxyphenyl)methanamine, and the molecular formula is C8H11NO, Synthetic Route of 6850-57-3.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem