Frein, Jeffrey D. published the artcileNew Sources of Chemical Diversity Inspired by Biosynthesis: Rational Design of a Potent Epothilone Analog, Safety of (+)-B-Methoxydiisopinocampheylborane, the publication is Organic Letters (2009), 11(15), 3186-3189, database is CAplus and MEDLINE.
A concise total synthesis of (14S)-14-methoxyepothilone D (I) was accomplished. (14S)-14-Methoxyepothilone D represents a conceptually novel example of polyketide analog design based on an alternative biogenetic pattern of extender units. The significant biol. activity observed for this compound provides a foundation to support studies designed to prepare derivatives of this type through fermentation of genetically engineered organisms expressing the epothilone PKS gene cluster.
Organic Letters published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Safety of (+)-B-Methoxydiisopinocampheylborane.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem