Journal of Organic Chemistry published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Recommanded Product: (+)-B-Methoxydiisopinocampheylborane.
Dinh, Tam Q. published the artcileAnalogs Incorporating trans-4-Hydroxy-L-proline That Reverse Multidrug Resistance Better than Hapalosin, Recommanded Product: (+)-B-Methoxydiisopinocampheylborane, the publication is Journal of Organic Chemistry (1997), 62(4), 790-791, database is CAplus.
Hydroxyproline-containing hapalosin analogs I [R = H, CH2C6H4OMe (PMB); R1 = H, CONHCH2Ph] were prepared in several steps starting from trans-4-hydroxy-L-proline. Whereas the PMB ether of hapalosin possesses substantially lower lower anti-multidrug resistance activity than hapalosin, analogs I (R = PMB, R1 = H; R = H, R1 = CONHCH2Ph) reverse multidrug resistance better than hapalosin, while I (R = = R1 = H; R = PMB, R1 = CONHCH2Ph) were less effective that hapalosin. These results suggest that a free hydroxyl and an aromatic group may be important in the multidrug resistance activity of hapalosin and its analogs.
Journal of Organic Chemistry published new progress about 99438-28-5. 99438-28-5 belongs to ethers-buliding-blocks, auxiliary class Chiral,Aliphatic cyclic hydrocarbon, name is (+)-B-Methoxydiisopinocampheylborane, and the molecular formula is C21H37BO, Recommanded Product: (+)-B-Methoxydiisopinocampheylborane.
Referemce:
https://en.wikipedia.org/wiki/Ether,
Ether | (C2H5)2O – PubChem